An eHealth decision-support tool to prioritize referral practices for genetic evaluation of patients with Wilms tumor

Cullinan N, et al. Int J Cancer. 2019.

Over 10% of children with Wilms tumor have an underlying cancer predisposition syndrome. There is an increasing demand for genetic evaluation and a need to rationalize genetic referrals for this population.

As part of the MIPOGG initiative, a decisional algorithm specific to Wilms tumor was developed. We tested the performance of this algorithm in 180 patients consecutively diagnosed with and/or treated for Wilms tumor at The Hospital for Sick Children (SickKids - Toronto, Canada).

We describe the contribution of elements in the algorithm that raise suspicion for a cancer predisposition syndrome.

Read the full article on PubMed (PMID: 31286500).