Retrospective evaluation of a decision-support algorithm (MIPOGG) for genetic referrals for children with neuroblastic tumors

Goudie C, et al. Pediatr Blood Cancer. 2018.

Neuroblastomas are associated with a variety of cancer predisposition syndromes, some of which are difficult to identify by physicians.

Through the MIPOGG initiative, we developed a decisional algorithm to identify which patients with neuroblastoma have an increased likelihood of a cancer predisposition syndrome. We assessed the algorithm's performance in a retrospective series of 209 children diagnosed and/or treated at the Hospital for Sick Children (SickKids - Toronto, Canada).

Read the full article on PubMed (PMID: 30117275).